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Journal of Clinical Microbiology, May 2004, p. 2347-2349, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2347-2349.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Posttransplantation Disseminated Coccidioidomycosis Acquired from Donor Lungs

Melissa B. Miller,1* Ryan Hendren,2 and Peter H. Gilligan1,2,3

Clinical Microbiology-Immunology Laboratories, University of North Carolina Hospitals,1 Departments of Pathology and Laboratory Medicine,2 Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina 275143

Received 13 November 2003/ Returned for modification 30 January 2004/ Accepted 9 February 2004

A North Carolinian developed fatal coccidioidomycosis immediately after bilateral lung transplantation. The donor had previously traveled to Mexico, and the recipient had no travel history to an area where Coccidioides immitis is endemic. Immunosuppresive therapy of the transplant recipient likely reactivated latent Coccidioides infection in the donor lungs, leading to posttransplant coccidioidomycosis.

* Corresponding author. Mailing address: Clinical Microbiology-Immunology Laboratories, University of North Carolina Hospitals, 101 Manning Dr., Chapel Hill, NC 27514. Phone: (919) 966-8312. Fax: (919) 966-0486. E-mail: mbmiller{at}unch.unc.edu.

Journal of Clinical Microbiology, May 2004, p. 2347-2349, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2347-2349.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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