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Journal of Clinical Microbiology, June 2004, p. 2833-2835, Vol. 42, No. 6
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.6.2833-2835.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Evaluation of a New Particle Gel Immunoassay for Determination of Antibodies against Treponema pallidum

Bruno L. Schmidt*

Department of Dermatology, Hospital of the City of Vienna—Lainz, A-1130 Vienna, Austria

Received 10 October 2003/ Returned for modification 24 November 2003/ Accepted 22 February 2004

A new particle gel immunoassay (DiaMed AG, Cressier sur Morat, Switzerland) with three recombinant Treponema pallidum antigens was evaluated with serum samples from patients with syphilis (n = 124) and patients without syphilis (n = 490). It proved to be a simple, rapid (20 min), and useful test with sensitivity, specificity, and positive and negative predictive values of 91.9, 99.8, 99.2, and 98%, respectively.

* Mailing address: Department of Dermatology, Hospital of the City of Vienna—Lainz, Wolkersbergenstr. 1, A-1130 Vienna, Austria. Phone: 431 80110 2536. Fax: 431 80110 2828. E-mail: bruno.schmidt{at}kavwien.at.

Journal of Clinical Microbiology, June 2004, p. 2833-2835, Vol. 42, No. 6
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.6.2833-2835.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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