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Journal of Clinical Microbiology, July 2004, p. 3298-3299, Vol. 42, No. 7
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.7.3298-3299.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Cloning and Characterization of Trichophyton rubrum Genes Encoding Actin, Tri r2, and Tri r4

Jimin Gao and Akira Takashima*

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9069

Received 30 January 2004/ Returned for modification 28 March 2004/ Accepted 11 April 2004

The three structural genes of Trichophyton rubrum encoding actin (3,429 bp) and two antigens, Tri r2 (2,950 bp) and Tri r4 (3,988 bp), were cloned and characterized. They contained six, four, and five exons, respectively. The T. rubrum actin protein sequence revealed extremely high homology to other fungal actins.

* Corresponding author. Mailing address: Department of Dermatology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9069. Phone: (214) 648-3419. Fax: (214) 648-3472. E-mail: akira.takashima{at}utsouthwestern.edu.

Journal of Clinical Microbiology, July 2004, p. 3298-3299, Vol. 42, No. 7
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.7.3298-3299.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kaufman, G., Berdicevsky, I., Woodfolk, J. A., Horwitz, B. A. (2005). Markers for Host-Induced Gene Expression in Trichophyton Dermatophytosis. Infect. Immun. 73: 6584-6590 [Abstract] [Full Text]  


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