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Journal of Clinical Microbiology, September 2004, p. 4303-4306, Vol. 42, No. 9
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.9.4303-4306.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Usefulness of the GenoType MTBC Assay for Differentiating Species of the Mycobacterium tuberculosis Complex in Cultures Obtained from Clinical Specimens

Elvira Richter,1* Michael Weizenegger,2 Anne-Marie Fahr,2 and Sabine Rüsch-Gerdes1

Forschungszentrum Borstel, National Reference Center for Mycobacteria, Borstel,1 Department of Microbiology, Laboratory Group, Heidelberg, Germany2

Received 22 January 2004/ Returned for modification 27 February 2004/ Accepted 13 May 2004

A novel DNA strip assay, GenoType MTBC, was evaluated for differentiation of Mycobacterium tuberculosis complex species from 77 positive liquid cultures in clinical practice. Species identification (M. tuberculosis [71 strains], Mycobacterium bovis subsp. bovis [5 strains], and Mycobacterium africanum subtype I [1 strain]) results were identical to conventional results. The sensitivity was slightly higher for this test than for the AccuProbe assay.

* Corresponding author. Mailing address: Forschungszentrum Borstel, National Reference Center for Mycobacteria, Parkallee 18, 23845 Borstel, Germany. Phone: (49) 4537-188760. Fax: (49) 4537-188311. E-mail: erichter{at}fz-borstel.de.

Journal of Clinical Microbiology, September 2004, p. 4303-4306, Vol. 42, No. 9
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.9.4303-4306.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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