This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Stradomska, T. J.
Right arrow Articles by Dzierzanowska, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stradomska, T. J.
Right arrow Articles by Dzierzanowska, D.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, October 2005, p. 5351-5354, Vol. 43, No. 10
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.10.5351-5354.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Urinary D-Arabinitol/L-Arabinitol Levels in Infants Undergoing Long-Term Antibiotic Therapy

Teresa J. Stradomska,1* Bogumila Bobula-Milewska,2 Anna Bauer,2 Zbigniew Mielniczuk,1 Maria Dabkowska,3 Malgorzata Syczewska,4 and Danuta Dzierzanowska3

Department of Laboratory Diagnostics,1 Infant Department,2 Department of Clinical Microbiology,3 Department of Pediatric Rehabilitation, The Children's Memorial Health Institute, Al. Dzieci Polskich 20, 04-736 Warsaw, Poland4

Received 10 November 2004/ Returned for modification 25 December 2004/ Accepted 6 July 2005

Long-term antibiotic therapy is one of the main risk factors for mycosis. The urinary D-arabinitol/L-arabinitol (D-/L-ARA) ratio (a biomarker of several Candida species) was determined by gas chromatography with an electron capture detector in samples from 51 infants undergoing long-term antibiotic therapy. Although 47 of these children had higher D-/L-ARA ratios than healthy controls (P < 0.0003), their values nonetheless remained within upper-normal limits (D-/L-ARA ratio of <3.6). Four children with suspected invasive candidiasis had above-normal ratios that normalized with fluconazole treatment.

* Corresponding author. Mailing address: The Children's Memorial Health Institute, Al. Dzieci Polskich 20, 04-736 Warsaw, Poland. Phone: 48-22-8151638. Fax: 48-22-815-1313. E-mail: address: jstradomska{at}op.pl.

Journal of Clinical Microbiology, October 2005, p. 5351-5354, Vol. 43, No. 10
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.10.5351-5354.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»