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Journal of Clinical Microbiology, December 2005, p. 6133-6135, Vol. 43, No. 12
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.12.6133-6135.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Comparison of the Binax NOW Flu A Enzyme Immunochromatographic Assay and R-Mix Shell Vial Culture for the 2003-2004 Influenza Season

Robert C. Fader*

Scott and White Memorial Hospital and the Texas A&M University Health Science Center, Temple, Texas 76508

Received 1 July 2005/ Returned for modification 17 August 2005/ Accepted 22 September 2005

The Binax NOW Flu A enzyme immunochromatographic assay was compared to viral culture with R-Mix shell vials for 455 nasal-wash or nasal-aspirate specimens. The overall sensitivity, specificity, positive predictive value, and negative predictive value of the assay were 64.9%, 98.4%, 89.3%, and 93.2%, respectively. However, the assay sensitivity decreased significantly with increasing patient age.

* Mailing address: Microbiology, Scott and White Memorial Hospital, 2401 South 31st Street, Temple, TX 76508. Phone: (254) 724-2714. Fax: (254) 724-8776. E-mail: rfader{at}swmail.sw.org.

Journal of Clinical Microbiology, December 2005, p. 6133-6135, Vol. 43, No. 12
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.12.6133-6135.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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