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Journal of Clinical Microbiology, July 2005, p. 3447-3449, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3447-3449.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Human Clinical Isolates of Corynebacterium diphtheriae and Corynebacterium ulcerans Collected in Canada from 1999 to 2003 but Not Fitting Reporting Criteria for Cases of Diphtheria

Leanne M. DeWinter,1* Kathryn A. Bernard,1 and Marc G. Romney2

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada R3E 3R2,1 Division of Medical Microbiology, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada2

Received 23 December 2004/ Returned for modification 8 February 2005/ Accepted 28 February 2005

A 5-year collection of Corynebacterium diphtheriae and Corynebacterium ulcerans human clinical isolates yielded nine isolates from blood cultures of patients with invasive infections, stressing the importance of C. diphtheriae as a serious blood-borne pathogen. Seven percent of C. diphtheriae and 100% of C. ulcerans isolates produced diphtheria toxin, demonstrating that toxigenic corynebacteria continue to circulate.

* Corresponding author. Mailing address: National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington St., Winnipeg, Manitoba, Canada R3E 3R2. Phone: (204) 789-2137. Fax: (204) 789-5009. E-mail: leanne_dewinter{at}phac-aspc.gc.ca.

Journal of Clinical Microbiology, July 2005, p. 3447-3449, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3447-3449.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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