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Journal of Clinical Microbiology, July 2005, p. 3471-3473, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3471-3473.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Possible Tick-Borne Human Enterovirus Resulting in Aseptic Meningitis

Eric C. Freundt, Douglas C. Beatty, Teresa Stegall-Faulk, and Stephen M. Wright^*

Middle Tennessee State University, Murfreesboro, Tennessee 37132

Received 14 December 2004/ Returned for modification 31 January 2005/ Accepted 9 March 2005

Enterovirus-specific genetic sequences were isolated from two Amblyomma americanum tick pools. Identical genetic sequences were later obtained from cerebrospinal fluid of a patient with aseptic meningitis and a recent history of tick attachment. These observations suggest the possibility of an emerging tick-borne human enterovirus associated with aseptic meningitis.

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* Corresponding author. Mailing address: Department of Biology, Box 60, Middle Tennessee State University, Murfreesboro, TN 37132. Phone: (615) 898-2056. Fax: (615) 898-5093. E-mail: smwright{at}mtsu.edu.

Present address: Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.

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Journal of Clinical Microbiology, July 2005, p. 3471-3473, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3471-3473.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.