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Journal of Clinical Microbiology, July 2005, p. 3484-3486, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3484-3486.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Frequent Detection of Epstein-Barr Virus and Cytomegalovirus but Not JC Virus DNA in Cerebrospinal Fluid Samples from Human Immunodeficiency Virus-Infected Patients in Northern Thailand

Archawin Rojanawiwat,1,2 Toshiyuki Miura,2 Hansa Thaisri,1 Panita Pathipvanich,3 Sittichai Umnajsirisuk,3 Tomohiko Koibuchi,2 Suthon Vongsheree,1 Aikichi Iwamoto,2 Koya Ariyoshi,4* and Pathom Sawanpanyalert1

National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand,1 Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan,2 Day Care Center, Lampang Hospital, Lampang, Thailand,3 AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan4

Received 18 August 2004/ Returned for modification 18 October 2004/ Accepted 27 February 2005

Applying nested-PCRs, we frequently detected DNA of Epstein-Barr virus and cytomegalovirus but not JC virus in cerebrospinal fluid samples from 140 human immunodeficiency virus-infected patients with central nervous system symptoms in northern Thailand. Despite the low incidence of primary central nervous system lymphoma or cytomegalovirus encephalitis among Thai AIDS patients, Epstein-Barr virus and cytomegalovirus infections in the central nervous system are common.

* Corresponding author. Mailing address: Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan. Phone: 81 (0) 95-849-7842. Fax: 81 (0) 95-849-7843. E-mail: kari{at}net.nagasaki-u.ac.jp. Address reprint requests to Archawin Rojanawiwat, National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Soi Bamrasnaradura, Tiwanon Road, Nonthaburi 11000, Thailand. E-mail: archawin191{at}yahoo.com.

Journal of Clinical Microbiology, July 2005, p. 3484-3486, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3484-3486.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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