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Journal of Clinical Microbiology, July 2005, p. 3491-3493, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3491-3493.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Molecular Evidence that Nasal Carriage of Staphylococcus aureus Plays a Role in Respiratory Tract Infections of Critically Ill Patients

Philippe Corne,1,2* Hélène Marchandin,3 Olivier Jonquet,1 Josiane Campos,3 and Anne-Laure Bañuls2

Service de Réanimation Médicale, Hôpital Gui de Chauliac,1 Laboratoire de Génétique et Evolution des Maladies Infectieuses (GEMI), Institut de Recherche pour le Développement (IRD),2 Laboratoire de Bactériologie, Hôpital Arnaud de Villeneuve, Montpellier, France3

Received 19 October 2004/ Returned for modification 17 November 2004/ Accepted 21 March 2005

The relationship between nasal Staphylococcus aureus carriage and lower respiratory tract infections was studied in 16 critically ill patients. S. aureus strains from nasal and bronchial samples were characterized by pulsed-field gel electrophoresis. In all but one case, nasal and bronchial strains were genetically identical in the same patients.

* Corresponding author. Mailing address: Service de Réanimation, Médicale Assistance Respiratoire, Hôpital Gui de Chauliac, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France. Phone: 00 33 04 67 41 62 26. Fax: 00 33 04 67 41 62 99. E-mail: p-corne{at}chu-montpellier.fr.

Journal of Clinical Microbiology, July 2005, p. 3491-3493, Vol. 43, No. 7
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.7.3491-3493.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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