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Journal of Clinical Microbiology, August 2005, p. 4159-4162, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4159-4162.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Oral Candida Isolates Colonizing or Infecting Human Immunodeficiency Virus-Infected and Healthy Persons in Mexico

Luis Octavio Sánchez-Vargas,1,2 Natalia Guadalupe Ortiz-López,1 María Villar,1 María Dolores Moragues,3 José Manuel Aguirre,4 Miguel Cashat-Cruz,5 Jose Luis Lopez-Ribot,6 Luis Alberto Gaitán-Cepeda,2 and Guillermo Quindós1*

Laboratorio de Micología Médica, Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Spain,1 Facultad de Odontología, Universidad Nacional Autónoma de México, México DF, México,2 Laboratorio de Micología Médica, Departamento de Enfermería I, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Spain,3 Cátedra de Medicina Bucal, Departamento de Estomatología, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Spain,4 Departamento de Epidemiología, Hospital Infantil de México Dr. Federico Gómez, México DF, Mexico,5 Department of Medicine, Division of Infectious Diseases, South Texas Centers for Biology in Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas6

Received 9 February 2005/ Accepted 17 April 2005

Oral yeast carriage was studied in 312 Mexican subjects. Candida albicans was the most frequent species, but other Candida spp. were isolated from 16.5 to 38.5% of patients. Colonization did not correlate with CD4+ number or viral load, but highly active antiretroviral therapy reduced the frequency of candidiasis. Most isolates were susceptible to fluconazole, but 10.8% were resistant to one or more azoles.

* Corresponding author. Mailing address: Laboratorio de Micología Médica, Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Spain. Phone: 34946012854. Fax:34946013400. E-mail: guillermo.quindos{at}ehu.es.

Journal of Clinical Microbiology, August 2005, p. 4159-4162, Vol. 43, No. 8
0095-1137/05/$08.00+0     doi:10.1128/JCM.43.8.4159-4162.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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