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Journal of Clinical Microbiology, August 2005, p. 4172-4174, Vol. 43, No. 8
0095-1137/05/$08.00+0 doi:10.1128/JCM.43.8.4172-4174.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Department of Clinical Chemistry and Microbiology, University of Damascus, Syria,1 Department of Virology, University of Saarland Medical School, Homburg/Saar, Germany2
Received 31 March 2005/ Returned for modification 10 May 2005/ Accepted 14 May 2005
HSV-1 DNA was detected in 32 (30%) of 106 cerebrospinal fluid samples from patients with encephalitis. Cytomegalovirus, varicella-zoster virus, and human herpesvirus 6 (HHV-6) DNAs were each detected in three patients (3%); herpes simplex virus type 2 (HSV-2) and HHV-7 PCRs were negative. HSV detection was associated with seizure (P = 0.02), especially focal seizure (P = 0.0002), and pathological computed tomography (P = 0.02) with focal lesions (P = 0.0004).
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