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Journal of Clinical Microbiology, January 2006, p. 283-286, Vol. 44, No. 1
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.1.283-286.2006

CASE REPORT

Specimens from a Vesicular Lesion Caused by Molluscum Contagiosum Virus Produced a Cytopathic Effect in Cell Culture That Mimicked That Produced by Herpes Simplex Virus

Constance A. Bell,1* Allison P. Eberly,1 Geraldine Takata,1 Raelene K. Combs,1 Nathan E. Deweese,2 and A. Christian Whelen1

Department of Pathology and Area Laboratory Services, Tripler Army Medical Center, Honolulu, Hawaii,1 Department of Family Practice, United States Army Health Clinic Schofield Barracks, Schofield Barracks, Hawaii2

Received 28 February 2005/ Returned for modification 20 July 2005/ Accepted 10 October 2005

Infection with molluscum contagiosum virus, a poxvirus, normally has a typical clinical presentation; therefore, laboratory confirmation is infrequently sought and the virus is rarely isolated in culture. As reported herein, viral culture of specimens from atypical lesions may produce an abortive infection in limited cell lines and a cytopathic effect suggestive of herpes simplex virus.


* Corresponding author. Present address: U.S. Army Dental and Trauma Research Detachment, 310B B St., Bldg. 1H, Great Lakes, IL 60088. Phone: (847) 688-7373, ext. 232. Fax: (847) 688-7872. E-mail: constance.bell{at}us.army.mil.


Journal of Clinical Microbiology, January 2006, p. 283-286, Vol. 44, No. 1
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.1.283-286.2006