This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ködmön, C.
Right arrow Articles by Somoskövi, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ködmön, C.
Right arrow Articles by Somoskövi, A.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, November 2006, p. 4258-4261, Vol. 44, No. 11
0095-1137/06/$08.00+0     doi:10.1128/JCM.01254-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Molecular Epidemiology of Drug-Resistant Tuberculosis in Hungary{triangledown}

Csaba Ködmön,1 Stefan Niemann,2 Judit Lukács,3 Éva Sör,3 Sándor Dávid,4 and Ákos Somoskövi3*

National Public Health and Medical Officers Service, Miskolc, Hungary,1 Reference Center for Mycobacteria, Forschungszentrum Borstel, Borstel, Germany,2 Department of Respiratory Medicine, School of Medicine, Semmelweis University, Budapest, Hungary,3 Korányi National Institute for Tuberculosis and Respiratory Medicine, Budapest, Hungary4

Received 19 June 2006/ Returned for modification 23 August 2006/ Accepted 30 August 2006

Sixty-eight drug-resistant Mycobacterium tuberculosis isolates (44.2% of all resistant cases) were analyzed by IS6110 restriction fragment length polymorphism fingerprinting and spoligotyping to provide a deeper insight into the status of drug-resistant tuberculosis in Hungary. A total of 54.4% of the drug-resistant cases and 75% of the multidrug-resistant cases could be clustered. Analysis of the spoligotyping patterns of the strains revealed a high rate (66.2%) of infection by the Haarlem genotype, while none of the patients were infected by the Beijing genotype. The magnitude and the dynamics of drug-resistant tuberculosis are underestimated in Hungary.

* Corresponding author. Mailing address: Department of Respiratory Medicine, School of Medicine, Semmelweis University, P.O. Box 250, 1536 Budapest 114, Hungary. Phone: 36-309-633-398. Fax: 36-1-214-2498. E-mail: akos{at}pulm.sote.hu.

{triangledown} Published ahead of print on 13 September 2006.

Journal of Clinical Microbiology, November 2006, p. 4258-4261, Vol. 44, No. 11
0095-1137/06/$08.00+0     doi:10.1128/JCM.01254-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»