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Journal of Clinical Microbiology, February 2006, p. 592-594, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.592-594.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Use of Cefoxitin-Based Selective Broth for Improved Detection of Methicillin-Resistant Staphylococcus aureus

Hong Fang* and Göran Hedin

Department of Clinical Bacteriology, Karolinska University Hospital, Huddinge, Karolinska Institute, SE-141 86 Stockholm, Sweden

Received 1 November 2005/ Accepted 3 November 2005

A cefoxitin-based selective broth was evaluated for its efficiency in detecting methicillin-resistant Staphylococcus aureus (MRSA) by the use of laboratory reference strains, clinical isolates of different clones, and clinical samples. The cefoxitin-based broth was proved to be more sensitive and rapid for the detection of MRSA strains, especially heterogeneously resistant strains, than the oxacillin-based broth.

* Corresponding author. Mailing address: Laboratory of Clinical Bacteriology, F82, Karolinska University Hospital, Huddinge, Stockholm SE-141 86, Sweden. Phone: 46 8 58581357. Fax: 46 8 58581080. E-mail: hong.fang{at}karolinska.se.

Journal of Clinical Microbiology, February 2006, p. 592-594, Vol. 44, No. 2
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.2.592-594.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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