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Journal of Clinical Microbiology, March 2006, p. 1169-1171, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1169-1171.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Usefulness of Eschar PCR for Diagnosis of Scrub Typhus

Seung-Hyun Lee,1 Dong-Min Kim,2* Young Shin Cho,3 Sung Ho Yoon,3 and Soo Kyoung Shim4

Department of Pediatrics, Seonam University College of Medicine, Gwangju,1 Division of Infectious Disease,2 Department of Internal Medicine, Chosun University College of Medicine, Clinical Research Institute, Gwangju,3 Korea Center for Disease Control and Prevention, Seoul, South Korea4

Received 1 April 2005/ Returned for modification 1 August 2005/ Accepted 21 December 2005

We report here on the case of a child who was infected with scrub typhus, and we made the diagnosis according to the serology and by performing PCRs on the child's eschar. The patient was treated with azithromycin, and he did not experience any complications. Performing nested PCR on the eschar might be both a rapid diagnostic test for scrub typhus in the early acute stage and a differential test as to whether or not a scab is a scrub typhus eschar.


* Corresponding author. Mailing address: Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju, 501-717, Republic of Korea. Phone: 82-62-220-3108. Fax: 82-62-234-9653. E-mail: drongkim{at}chosun.ac.kr.


Journal of Clinical Microbiology, March 2006, p. 1169-1171, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1169-1171.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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