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Journal of Clinical Microbiology, March 2006, p. 1172-1174, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1172-1174.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Treatment Failure Due to Emergence of Resistance to Carbapenem during Therapy for Shewanella algae Bacteremia

Dong-Min Kim,1,{dagger} Cheol-In Kang,1 Chang Seop Lee,1 Hong-Bin Kim,1 Eui-Chong Kim,2,3 Nam Joong Kim,1,3 Myoung-don Oh,1,3* and Kang-Won Choe1,3

Departments of Internal Medicine,1 Laboratory Medicine, Seoul National University College of Medicine,2 Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea3

Received 13 September 2005/ Returned for modification 14 October 2005/ Accepted 23 November 2005

We describe a case of bacteremia due to imipenem-susceptible Shewanella algae. Despite treatment with imipenem, the patient developed a spinal epidural abscess, from which imipenem-resistant S. algae was isolated. The development of resistance should be monitored when S. algae infection is treated with imipenem, even though the strain is initially susceptible to imipenem.


* Corresponding author. Mailing address: Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Republic of Korea. Phone: 82-2-760-2945. Fax: 82-2-747-6090. E-mail: mdohmd{at}snu.ac.kr.

{dagger} Present address: Department of Internal Medicine, Chosun University College of Medicine, Clinical Research Institute, Chosun University Hospital, Gwang-ju, Republic of Korea.


Journal of Clinical Microbiology, March 2006, p. 1172-1174, Vol. 44, No. 3
0095-1137/06/$08.00+0     doi:10.1128/JCM.44.3.1172-1174.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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