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Journal of Clinical Microbiology, June 2006, p. 2229-2232, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.02569-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Phylogenetic Analysis of Previously Nontypeable Hepatitis C Virus Isolates from Argentina{dagger}

María Inés Gismondi,1* Pablo Daniel Becker,2 Pamela Valva,1 Carlos Alberto Guzmán,2 and María Victoria Preciado1

Laboratorio de Virología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD Ciudad de Buenos Aires, Argentina,1 Department of Vaccinology, GBF-German Research Centre for Biotechnology, Mascheroder Weg 1, D-38124 Braunschweig, Germany2

Received 9 December 2005/ Returned for modification 6 February 2006/ Accepted 21 March 2006

Phylogenetic analysis of hepatitis C virus isolates from Argentina that were previously nontypeable by restriction fragment length polymorphism (RFLP) analysis revealed that they belong to genotype 1a. A substitution at position 107 (G->A), which is the landmark of these strains, was shown to be distributed among isolates worldwide. The RFLP patterns obtained for these isolates should be added to the ones reported for genotype 1 isolates.

* Corresponding author. Mailing address: Laboratorio de Virología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD Ciudad de Buenos Aires, Argentina. Phone: 5411-4964-3118. Fax: 5411-4962-6770. E-mail: migismondi{at}yahoo.com.ar.

{dagger} Supplemental material for this article may be found at http://jcm.asm.org/.

Journal of Clinical Microbiology, June 2006, p. 2229-2232, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.02569-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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