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Journal of Clinical Microbiology, June 2006, p. 2300-2303, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.00152-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Human Metapneumovirus Infection in a Hematopoietic Stem Cell Transplant Recipient with Relapsed Multiple Myeloma and Rapidly Progressing Lung Cancer

B. Huck,1 M. Egger,2 H. Bertz,2 G. Peyerl-Hoffman,2 W. V. Kern,2 D. Neumann-Haefelin,1 and V. Falcone1*

Department of Virology,1 Department of Medicine, University Hospital Freiburg, Freiburg, Germany2

Received 24 January 2006/ Returned for modification 21 March 2006/ Accepted 4 April 2006

Human metapneumovirus (HMPV) was isolated from a 63-year-old multiple myeloma patient who had undergone hematopoietic stem cell transplantation and who presented with lower respiratory tract infection several weeks prior to the diagnosis of lung cancer. The isolate was phylogenetically and biologically characterized and compared to HMPV prototypes and recent pediatric isolates. Remarkably, it belonged to the novel genomic subgroup A2b.

* Corresponding author. Mailing address: Department of Virology, Institute for Medical Microbiology and Hygiene, University Hospital Freiburg, Hermann-Herder-Str. 11, 79104 Freiburg, Germany. Phone: 49-761-2036618. Fax: 49-761-2036626. E-mail: valeria.kapper-falcone{at}uniklinik-freiburg.de.

Journal of Clinical Microbiology, June 2006, p. 2300-2303, Vol. 44, No. 6
0095-1137/06/$08.00+0     doi:10.1128/JCM.00152-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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