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Journal of Clinical Microbiology, July 2006, p. 2579-2580, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.00818-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Voriconazole Susceptibilities of Dermatophyte Isolates Obtained from a Worldwide Tinea Capitis Clinical Trial

M. Ghannoum,1* N. Isham,1 and D. Sheehan2

Center for Medical Mycology, University Hospitals of Cleveland/Case Western Reserve University, Cleveland, Ohio,1 Pfizer, Inc., New York, New York2

Received 17 April 2006/ Accepted 11 May 2006

In this study, the voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis trial were compared to their susceptibilities to fluconazole and griseofulvin. The MIC ranges of voriconazole, fluconazole, and griseofulvin, were 0.002 to 0.06 µg/ml, 0.25 to 32 µg/ml, and 0.125 to 2.0 µg/ml, respectively.

* Corresponding author. Mailing address: Center for Medical Mycology, University Hospitals of Cleveland/Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106. Phone: (216) 844-8580. Fax: (216) 844-1076. E-mail: mahmoud.ghannoum{at}uhhs.com.

Journal of Clinical Microbiology, July 2006, p. 2579-2580, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.00818-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • White, T. C., Oliver, B. G., Graser, Y., Henn, M. R. (2008). Generating and Testing Molecular Hypotheses in the Dermatophytes. Eukaryot Cell 7: 1238-1245 [Full Text]  


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