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Journal of Clinical Microbiology, July 2006, p. 2581-2583, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.00510-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Hospital-Acquired Bordetella bronchiseptica Infection following Hematopoietic Stem Cell Transplantation

Elizabeth S. Huebner,1,{dagger} Brian Christman,1 Stephen Dummer,1 Yi-Wei Tang,1,2* and Stacey Goodman1

Departments of Medicine,1 Pathology, Vanderbilt University Medical Center, Nashville, Tennessee2

Received 8 March 2006/ Returned for modification 2 April 2006/ Accepted 11 May 2006

Two patients who had undergone nonmyeloablative allogeneic stem cell transplantation 53 and 112 days earlier and were being monitored at the same transplant center developed severe Bordetella bronchiseptica infections within 3 days of each other. Pulsed-field gel electrophoresis analysis indicated that the isolates from the two cases were identical. Neither patient had had direct contact with animals since transplantation. These findings strongly support nosocomial transmission of B. bronchiseptica.


* Corresponding author. Mailing address: Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232-5310. Phone: (615) 322-2035. Fax: (615) 343-8420. E-mail: yiwei.tang{at}vanderbilt.edu.

{dagger} Present address: University of Washington, Seattle, Washington.


Journal of Clinical Microbiology, July 2006, p. 2581-2583, Vol. 44, No. 7
0095-1137/06/$08.00+0     doi:10.1128/JCM.00510-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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