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Journal of Clinical Microbiology, August 2006, p. 2963-2966, Vol. 44, No. 8
0095-1137/06/$08.00+0     doi:10.1128/JCM.00341-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Comparison of the LCx Human Immunodeficiency Virus (HIV) RNA Quantitative, RealTime HIV, and COBAS AmpliPrep-COBAS TaqMan Assays for Quantitation of HIV Type 1 RNA in Plasma

Vincent Foulongne, Brigitte Montes, Marie-Noelle Didelot-Rousseau, and Michel Segondy*

Division of Virology, Department of Infectious Diseases, Montpellier University Hospital, 34295 Montpellier, France

Received 16 February 2006/ Returned for modification 7 April 2006/ Accepted 16 May 2006

The LCx human immunodeficiency virus (HIV) RNA Quantitative, RealTime HIV, and COBAS AmpliPrep-COBAS TaqMan assays for HIV type 1 (HIV-1) were compared for their abilities to quantitate HIV-1 RNA in plasma. High degrees of correlation and agreement were observed between the assays. Differences in HIV-1 RNA levels according to HIV-1 subtypes did not reach statistical significance.

* Corresponding author. Mailing address: Laboratoire de Virologie, Hôpital Saint-Eloi, 80 Avenue Augustin Fliche, 34295 Montpellier Cedex 05, France. Phone: (33) 467 337 127. Fax: (33) 467 337 793. E-mail: m-segondy{at}chu-montpellier.fr.

Journal of Clinical Microbiology, August 2006, p. 2963-2966, Vol. 44, No. 8
0095-1137/06/$08.00+0     doi:10.1128/JCM.00341-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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