This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Martínez, M.
Right arrow Articles by Gutiérrez, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Martínez, M.
Right arrow Articles by Gutiérrez, C.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, August 2006, p. 2967-2969, Vol. 44, No. 8
0095-1137/06/$08.00+0     doi:10.1128/JCM.00754-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Impact of Laboratory Cross-Contamination on Molecular Epidemiology Studies of Tuberculosis

Miguel Martínez,6 Darío García de Viedma,1* María Alonso,1 Sandra Andrés,1 Emilio Bouza,1 Teresa Cabezas,2 Isabel Cabeza,2 Armando Reyes,6 Waldo Sánchez-Yebra,6 Manuel Rodríguez,4 M. Isabel Sánchez,5 M. Cruz Rogado,2 Rosa Fernández,5 Teresa Peñafiel,5 Juan Martínez,7 Pilar Barroso,3 M. Ángeles Lucerna,2 L. Felipe Diez,6 and Carmelo Gutiérrez3

Hopital Gregorio Marañón, Madrid, Spain,1 Complejo Hospitalario Torrecárdenas, Almería, Spain,6 Empresa Pública Hospital de Poniente, El Ejido, Almería, Spain,2 Distrito Atención Primaria Levante-Alto Almanzora, Huercal-Overa, Almería, Spain,3 Unidad de Tuberculosis de Poniente, Santa María del Águila, Almería, Spain,5 Hospital la Inmaculada, Huercal-Overa, Almería, Spain,4 Centro Penitenciario el Acebuche, Almería, Spain7

Received 10 April 2006/ Returned for modification 18 May 2006/ Accepted 19 May 2006

Laboratory cross-contamination by Mycobacterium tuberculosis is known to be responsible for the misdiagnosis of tuberculosis, but its impact on other contexts has not been analyzed. We present the findings of a molecular epidemiology analysis in which the recent transmission events identified by a genotyping reference center were overestimated as a result of unnoticed laboratory cross-contamination in the original diagnostic laboratories.

* Corresponding author. Mailing address: Servicio de Microbiología y Enfermedades Infecciosas, Hospital Gregorio Marañón, c/ Dr. Esquerdo 46, 28007 Madrid, Spain. Phone: 34 91 4265104. Fax: 34 91 5044906. E-mail: dgviedma{at}microb.net.

Journal of Clinical Microbiology, August 2006, p. 2967-2969, Vol. 44, No. 8
0095-1137/06/$08.00+0     doi:10.1128/JCM.00754-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»