This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mathet, V. L.
Right arrow Articles by Oubiña, J. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mathet, V. L.
Right arrow Articles by Oubiña, J. R.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, September 2006, p. 3435-3439, Vol. 44, No. 9
0095-1137/06/$08.00+0     doi:10.1128/JCM.00866-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Detection of Hepatitis B Virus (HBV) Genotype E Carried—Even in the Presence of High Titers of Anti-HBs Antibodies—by an Argentinean Patient of African Descent Who Had Received Vaccination against HBV

Verónica L. Mathet,1 María L. Cuestas,1 Vanesa Ruiz,1 María L. Minassian,1 Cintia Rivero,1 Julieta Trinks,1 Graciela Daleoso,2 Liliana M. León,2 Andrea Sala,3 Beatriz Libellara,4 Daniel Corach,3 and José R. Oubiña1*

Centro para el Estudio de Hepatitis Virales, Departamento de Microbiología, Facultad de Medicina, Universidad de Buenos Aires,1 Hospital Ramos Mejía,2 Laboratorio de Huellas Digitales y Cátedra de Genética Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires,3 Laboratorio de Biología Molecular, Hospital Italiano, Buenos Aires, Argentina4

Received 24 April 2006/ Returned for modification 2 June 2006/ Accepted 3 July 2006

Genotype E hepatitis B virus (HBV) was detected in two Argentine sisters exhibiting an African mitochondrial lineage. One of them (who had been vaccinated against HBV) exhibited anti-HBs cocirculating antibodies without HBsAg escape mutants, while her unvaccinated sister showed a D144A HBsAg escape mutant without anti-HBs antibodies. Both sisters carried an unusual L209V substitution within HBsAg.

* Corresponding author. Mailing address: Centro para el Estudio de Hepatitis Virales, Departamento Microbiología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155 Piso 11, 1121 Buenos Aires, Argentina. Phone: 54-11-5950-9500-2175. Fax: 54-11-4508-3705. E-mail: joubina{at}fmed.uba.ar.

Journal of Clinical Microbiology, September 2006, p. 3435-3439, Vol. 44, No. 9
0095-1137/06/$08.00+0     doi:10.1128/JCM.00866-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»