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Journal of Clinical Microbiology, January 2007, p. 234-236, Vol. 45, No. 1
0095-1137/07/$08.00+0     doi:10.1128/JCM.01867-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Serological Cross-Reactivity between Different Chlamydia-Like Organisms{triangledown}

Nicola Casson,1 José M. Entenza,2 and Gilbert Greub1*

Center for Research on Intracellular Bacteria, Institute of Microbiology,1 Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland2

Received 8 September 2006/ Accepted 12 October 2006

The serological cross-reactivity between different recently described Chlamydia-related organisms was determined. Mouse sera exhibited a strong reactivity against autologous antigen and closely related heterologous antigen but no cross-reactivity with distantly related species. These results are important to better interpret serological studies and assess the pathogenic role of these obligate intracellular bacteria.


* Corresponding author. Mailing address: Center for Research on Intracellular Bacteria, Institute of Microbiology, University of Lausanne, 1011 Lausanne, Switzerland. Phone: 4121/314.49.79. Fax: 4121/314.40.60. E-mail: gilbert.greub{at}chuv.ch.

{triangledown} Published ahead of print on 25 October 2006.


Journal of Clinical Microbiology, January 2007, p. 234-236, Vol. 45, No. 1
0095-1137/07/$08.00+0     doi:10.1128/JCM.01867-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • Borel, N., Casson, N., Entenza, J. M., Kaiser, C., Pospischil, A., Greub, G. (2009). Tissue microarray and immunohistochemistry as tools for evaluation of antibodies against Chlamydia-like bacteria. J Med Microbiol 58: 863-866 [Abstract] [Full Text]