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Journal of Clinical Microbiology, December 2007, p. 4064-4066, Vol. 45, No. 12
0095-1137/07/$08.00+0     doi:10.1128/JCM.01780-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Cavitary Disease and Quantitative Sputum Bacillary Load in Cases of Pulmonary Tuberculosis{triangledown}

Moises Palaci,1* Reynaldo Dietze,1 David Jamil Hadad,1 Fabiola Karla Corrêa Ribeiro,1 Renata Lyrio Peres,1 Solange Alves Vinhas,1 Ethel Leonor Noia Maciel,1 Valdério do Valle Dettoni,1 Libby Horter,2 W. Henry Boom,2 John L. Johnson,2 and Kathleen D. Eisenach3

Núcleo de Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, Brazil,1 Department of Medicine, Division of Infectious Diseases, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, Ohio,2 Departments of Pathology and Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas3

Received 6 September 2007/ Accepted 30 September 2007

We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease.

* Corresponding author. Mailing address: Núcleo de Doenças Infecciosas-Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468 Maruipe, Vitória, CEP 29040-091, Brazil. Phone and fax: 55 (27) 2122-7210. E-mail: mpalaci{at}ndi.ufes.br

{triangledown} Published ahead of print on 10 October 2007.

Journal of Clinical Microbiology, December 2007, p. 4064-4066, Vol. 45, No. 12
0095-1137/07/$08.00+0     doi:10.1128/JCM.01780-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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