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Journal of Clinical Microbiology, February 2007, p. 607-609, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.02099-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Usefulness of PCR-Restriction Fragment Length Polymorphism Typing of the Coagulase Gene To Discriminate Arbekacin-Resistant Methicillin-Resistant Staphylococcus aureus Strains{triangledown}

Keiko Ishino,1* Naofumi Tsuchizaki,1,2 Jun Ishikawa,1 and Kunimoto Hotta1

Department of Bioactive Molecules, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan,1 Japan Microbiological Clinic, Co., Ltd., 5-17-1, Okada, Atsugi, Kanagawa 243-0021, Japan2

Received 12 October 2006/ Accepted 5 December 2006

We compared the results of two typing methods for 678 strains of methicillin-resistant Staphylococcus aureus and methicillin-susceptible S. aureus. PCR-restriction fragment length polymorphism typing of the coagulase gene was a more reliable method than coagulase serotyping from the viewpoint of arbekacin resistance.

* Corresponding author. Mailing address: Department of Bioactive Molecules, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan. Phone: 81 3 5285 1111. Fax: 81 3 5285 1272. E-mail: ishino{at}nih.go.jp.

{triangledown} Published ahead of print on 13 December 2006.

Journal of Clinical Microbiology, February 2007, p. 607-609, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.02099-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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