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Journal of Clinical Microbiology, February 2007, p. 631-635, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.02188-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Vancomycin-Resistant Enterococcus faecalis Endocarditis: Linezolid Failure and Strain Characterization of Virulence Factors{triangledown}

Constantine Tsigrelis,1,2* Kavindra V. Singh,3,4 Thais D. Coutinho,2 Barbara E. Murray,3,4,5 and Larry M. Baddour1,2

Division of Infectious Diseases,1 Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905,2 Division of Infectious Diseases, Department of Medicine,3 Center for the Study of Emerging and Re-emerging Pathogens,4 Department of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, Texas 770305

Received 25 October 2006/ Returned for modification 27 November 2006/ Accepted 11 December 2006

Infective endocarditis due to vancomycin-resistant (VR) Enterococcus faecalis has only rarely been reported. We report a case of VR E. faecalis endocarditis that failed to respond to linezolid therapy, outline the virulence traits of the isolate, and review previously published cases of VR E. faecalis endocarditis.

* Corresponding author. Mailing address: Division of Infectious Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905. Phone: (507) 255-1980. Fax: (507) 255-7767. E-mail: tsigrelis.constantine{at}mayo.edu.

{triangledown} Published ahead of print on 20 December 2006.

Journal of Clinical Microbiology, February 2007, p. 631-635, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.02188-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Chowdhury, S. A., Arias, C. A., Nallapareddy, S. R., Reyes, J., Willems, R. J. L., Murray, B. E. (2009). A Trilocus Sequence Typing Scheme for Hospital Epidemiology and Subspecies Differentiation of an Important Nosocomial Pathogen, Enterococcus faecalis. J. Clin. Microbiol. 47: 2713-2719 [Abstract] [Full Text]  


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