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Journal of Clinical Microbiology, February 2007, p. 636-640, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.01907-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Mucor circinelloides Was Identified by Molecular Methods as a Cause of Primary Cutaneous Zygomycosis{triangledown}

Peter C. Iwen,1* Lynne Sigler,2 Rhonda K. Noel,1 and Alison G. Freifeld3

Department of Pathology and Microbiology,1 Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska,3 University of Alberta Microfungus Collection and Herbarium, Devonian Botanic Garden, Edmonton, Alberta, Canada2

Received 13 September 2006/ Returned for modification 19 October 2006/ Accepted 7 November 2006

A case of primary cutaneous zygomycosis caused by Mucor circinelloides is described. Histopathology showed typical hyphae along with chlamydospores. The isolate was identified by molecular and phenotypic methods. The utility of sequence analysis of the internal transcribed spacer region is highlighted; however, further studies are needed to assess species genetic heterogeneity.

* Corresponding author. Mailing address: Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198-6495. Phone: (402) 559-7774. Fax: (402) 559-4077. E-mail: piwen{at}unmc.edu.

{triangledown} Published ahead of print on 17 November 2006.

Journal of Clinical Microbiology, February 2007, p. 636-640, Vol. 45, No. 2
0095-1137/07/$08.00+0     doi:10.1128/JCM.01907-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Alvarez, E., Sutton, D. A., Cano, J., Fothergill, A. W., Stchigel, A., Rinaldi, M. G., Guarro, J. (2009). Spectrum of Zygomycete Species Identified in Clinically Significant Specimens in the United States. J. Clin. Microbiol. 47: 1650-1656 [Abstract] [Full Text]  
  • Khan, Z. U., Ahmad, S., Brazda, A., Chandy, R. (2009). Mucor circinelloides as a Cause of Invasive Maxillofacial Zygomycosis: an Emerging Dimorphic Pathogen with Reduced Susceptibility to Posaconazole. J. Clin. Microbiol. 47: 1244-1248 [Abstract] [Full Text]  


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