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Journal of Clinical Microbiology, April 2007, p. 1370-1372, Vol. 45, No. 4
0095-1137/07/$08.00+0     doi:10.1128/JCM.00920-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Zoonotic Vaccinia Virus Infection in Brazil: Clinical Description and Implications for Health Professionals{triangledown}

Giliane de Souza Trindade,1 Betania Paiva Drumond,1 Maria Isabel Maldonado Coelho Guedes,1 Juliana Almeida Leite,1,{dagger} Bruno Eduardo Fernandes Mota,1 Marco Antônio Campos,2 Flávio Guimarães da Fonseca,3 Maurício Lacerda Nogueira,4 Zélia Inês Portela Lobato,5 Cláudio Antônio Bonjardim,1 Paulo César Peregrino Ferreira,1* and Erna Geessien Kroon1

Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Caixa Postal 486, CEP 31270-901, Belo Horizonte, MG, Brazil,1 Laboratório de Imunopatologia, Centro de Pesquisas René Rachou-FIOCRUZ, Av. Augusto de Lima, 1715 Barro Preto CEP 30190-002, Belo Horizonte, MG, Brazil,2 Laboratório de Imunologia Celular e Molecular, Centro de Pesquisas René Rachou-FIOCRUZ, Av. Augusto de Lima, 1715 Barro Preto CEP 30190-002, Belo Horizonte, MG, Brazil,3 Laboratório de Pesquisas em Virologia, Departamento de Doenças Infecciosas e Parasitárias Faculdade de Medicina de São José do Rio Preto, Av. Brigadeiro Faria Lima, 5416 CEP 15090-000, São Jose do Rio Preto, SP, Brazil,4 Departamento de Medicina Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Caixa Postal, CEP 31270-901, Belo Horizonte, MG, Brazil5

Received 2 May 2006/ Returned for modification 21 November 2006/ Accepted 16 January 2007

Bovine vaccinia virus outbreaks have been occurring in different regions of Brazil. We report here the time course of natural human infection by vaccinia virus and describe important clinical and epidemiological aspects of this zoonotic infection. The diagnosis of vaccinia virus infection was based on clinical, serological, and molecular procedures.

* Corresponding author. Mailing address: Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais. Av. Antônio Carlos, 6627, Caixa Postal 486, CEP 31270-901, Belo Horizonte, MG, Brazil. Phone: 55 31 3499-2747. Fax: 55 31 3443-6482. E-mail: masc.egk{at}terra.com.br

{triangledown} Published ahead of print on 7 February 2007.

{dagger} Present address: Brazilian Agricultural Research Corp./Embrapa Dairy Cattle, Rua Eugênio do Nascimento, 610, Dom Bosco, CEP 36.038-330, Juiz de Fora, MG, Brazil.

Journal of Clinical Microbiology, April 2007, p. 1370-1372, Vol. 45, No. 4
0095-1137/07/$08.00+0     doi:10.1128/JCM.00920-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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