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Journal of Clinical Microbiology, June 2007, p. 2078-2081, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00096-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Tropheryma whipplei Infective Endocarditis as the Only Manifestation of Whipple's Disease{triangledown}

Mercedes Marín,* Patricia Muñoz, Mónica Sánchez, Marina del Rosal, Marta Rodríguez-Créixems, E. Bouza, on behalf of Grupo de Apoyo al Manejo de la Endocarditis Infecciosa del Hospital Gregorio Marañón, Madrid, Spain

Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain

Received 14 January 2007/ Returned for modification 13 February 2007/ Accepted 11 April 2007

Here we describe a case of infective endocarditis caused by Tropheryma whipplei in a patient with no other symptoms of Whipple's disease. The case was diagnosed using broad-range PCR and confirmed by specific PCRs. We review the cases of infective endocarditis presenting as the only manifestation of Whipple's disease reported in the literature.


* Corresponding author. Mailing address: Servicio de Microbiología Clínica y E. Infecciosas, Hospital General Universitario Gregorio Marañón, Dr. Esquerdo, 46, 28007 Madrid, Spain. Phone: 34 91 5868793. Fax: 34 91 5044906. E-mail: mmarin{at}microb.net

{triangledown} Published ahead of print on 19 April 2007.


Journal of Clinical Microbiology, June 2007, p. 2078-2081, Vol. 45, No. 6
0095-1137/07/$08.00+0     doi:10.1128/JCM.00096-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




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  • Mancini, F., Sbaragli, S., Colivicchi, G., Cassone, A., Ciervo, A. (2009). Fourteen Years of Severe Arthralgia in a Man without Gastrointestinal Symptoms: Atypical Whipple's Disease. J. Clin. Microbiol. 47: 492-495 [Abstract] [Full Text]