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Journal of Clinical Microbiology, July 2007, p. 2267-2269, Vol. 45, No. 7
0095-1137/07/$08.00+0     doi:10.1128/JCM.00369-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Rapid Identification of Staphylococcus aureus in Blood Cultures by Use of the Direct Tube Coagulase Test{triangledown}

Qinfang Qian,* Karen Eichelberger, and James E. Kirby

Division of Laboratory and Transfusion Medicine, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215

Received 16 February 2007/ Returned for modification 5 April 2007/ Accepted 11 May 2007

Direct tube coagulase testing for identification of Staphylococcus aureus from BACTEC culture broth showed a sensitivity, a specificity, and positive and negative predicative values of 34%, 100%, 100%, and 80.2% with 2 h of incubation and 65%, 98.7, 99.7%, and 88.6% with 4 h of incubation. Anaerobic blood culture contributed significantly to the detection of S. aureus.

* Corresponding author. Mailing address: Department of Pathology, Beth Israel Deaconess Medical Center, Yamins 309, 330 Brookline Avenue, Boston, MA 02215. Phone: (617) 667-4911. Fax: (617) 667-4533. E-mail: qqian{at}bidmc.harvard.edu

{triangledown} Published ahead of print on 23 May 2007.

Journal of Clinical Microbiology, July 2007, p. 2267-2269, Vol. 45, No. 7
0095-1137/07/$08.00+0     doi:10.1128/JCM.00369-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kerremans, J. J., Goessens, W. H. F., Verbrugh, H. A., Vos, M. C. (2008). Rapid Identification of Staphyloccocus aureus in Positive-Testing Blood Cultures by Slidex Staph Plus Agglutination Test. J. Clin. Microbiol. 46: 395-395 [Full Text]  
  • Lagace-Wiens, P. R. S., Alfa, M. J., Manickam, K., Karlowsky, J. A. (2007). Thermostable DNase Is Superior to Tube Coagulase for Direct Detection of Staphylococcus aureus in Positive Blood Cultures. J. Clin. Microbiol. 45: 3478-3479 [Full Text]  


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