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Journal of Clinical Microbiology, July 2007, p. 2278-2280, Vol. 45, No. 7
0095-1137/07/$08.00+0     doi:10.1128/JCM.00469-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Comparison of Two Versions of the IDI-MRSA Assay Using Charcoal Swabs for Prospective Nasal and Nonnasal Surveillance Samples{triangledown}

Sean X. Zhang,1 Steven J. Drews,2 Joanne Tomassi,4 and Kevin C. Katz1,3,4*

Department of Laboratory Medicine and Pathobiology, University of Toronto,1 Ontario Public Health Laboratories,2 Infection Prevention and Control,3 Department of Laboratory Medicine, North York General Hospital, Toronto, Ontario, Canada4

Received 1 March 2007/ Returned for modification 4 May 2007/ Accepted 11 May 2007

An updated IDI-MRSA assay version was released to address the assay's low positive predictive value (PPV). A prospective analysis of two assay versions indicated no significant improvement in the PPV. Colonization by methicillin-resistant Staphylococcus aureus in 24% of patients would not have been detected if only nasal samples had been tested, as approved, by this molecular method.

* Corresponding author. Mailing address: Department of Laboratory Medicine, North York General Hospital, 4001 Leslie St., Suite GW-33, Toronto M2K1E1, Canada. Phone: (416) 756-6130. Fax: (416) 756-6449. E-mail: kkatz{at}nygh.on.ca

{triangledown} Published ahead of print on 23 May 2007.

Journal of Clinical Microbiology, July 2007, p. 2278-2280, Vol. 45, No. 7
0095-1137/07/$08.00+0     doi:10.1128/JCM.00469-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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