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Journal of Clinical Microbiology, January 2008, p. 321-324, Vol. 46, No. 1
0095-1137/08/$08.00+0     doi:10.1128/JCM.02097-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Optochin Resistance among Streptococcus pneumoniae Strains Colonizing Healthy Children in Portugal{triangledown}

Sónia Nunes,1 Raquel Sá-Leão,1* and Hermínia de Lencastre1,2

Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal,1 Laboratory of Microbiology, The Rockefeller University, New York, New York2

Received 30 October 2007/ Accepted 5 November 2007

Two percent of 1,973 pneumococcus strains isolated from carriers since 2001 in Portugal were found to be optochin resistant. These strains belonged to eight serotypes (and some were nontypeable), and they had diverse genetic backgrounds. Novel optochin-resistant lineages were detected over time, suggesting that there was a continuous, although sporadic, emergence of optochin resistance.

* Corresponding author. Mailing address: Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Rua da Quinta Grande, 6, Oeiras, 2780-156 Oeiras, Portugal. Phone: 351 21 4469872. Fax: 351 21 4428766. E-mail: rsaleao{at}itqb.unl.pt

{triangledown} Published ahead of print on 21 November 2007.

Journal of Clinical Microbiology, January 2008, p. 321-324, Vol. 46, No. 1
0095-1137/08/$08.00+0     doi:10.1128/JCM.02097-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Richter, S. S., Heilmann, K. P., Dohrn, C. L., Riahi, F., Beekmann, S. E., Doern, G. V. (2008). Accuracy of Phenotypic Methods for Identification of Streptococcus pneumoniae Isolates Included in Surveillance Programs. J. Clin. Microbiol. 46: 2184-2188 [Abstract] [Full Text]  
  • Cortes, P. R., Orio, A. G. A., Regueira, M., Pinas, G. E., Echenique, J. (2008). Characterization of In Vitro-Generated and Clinical Optochin-Resistant Strains of Streptococcus pneumoniae Isolated from Argentina. J. Clin. Microbiol. 46: 1930-1934 [Abstract] [Full Text]  


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