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Journal of Clinical Microbiology, October 2008, p. 3498-3500, Vol. 46, No. 10
0095-1137/08/$08.00+0     doi:10.1128/JCM.00982-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Production of White Colonies on CHROMagar Candida Medium by Members of the Candida glabrata Clade and Other Species with Overlapping Phenotypic Traits{triangledown}

Justin A. Bishop,1 Nancy Chase,1,{dagger} Richard Lee,1 Cletus P. Kurtzman,2 and William G. Merz1*

Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland,1 Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, U.S. Department of Agriculture, Peoria, Illinois2

Received 21 May 2008/ Returned for modification 7 July 2008/ Accepted 25 July 2008

We hypothesized that species of the Candida glabrata clade and species with phenotypic traits that overlap those of C. glabrata would produce white colonies on CHROMagar Candida medium. Of 154 isolates (seven species) tested, C. bracarensis, C. nivariensis, C. norvegensis, C. glabrata, and C. inconspicua produced white colonies; the Pichia fermentans group and C. krusei did not. Many of these species are difficult to identify phenotypically; white colonies may signal the need for the use of molecular approaches.

* Corresponding author. Mailing address: Department of Pathology, The Johns Hopkins Medical Institutions, Meyer B1-193, 600 N. Wolfe St., Baltimore, MD 21112. Phone: (410) 955-5077. Fax: (410) 614-8087. E-mail: wmerz{at}jhmi.edu

{triangledown} Published ahead of print on 6 August 2008.

{dagger} Present address: Walter Reed Army Medical Center, 6900 Georgia Ave. NW, Washington, DC 20307.

Journal of Clinical Microbiology, October 2008, p. 3498-3500, Vol. 46, No. 10
0095-1137/08/$08.00+0     doi:10.1128/JCM.00982-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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