This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wong, W.-W.
Right arrow Articles by Li, S.-Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wong, W.-W.
Right arrow Articles by Li, S.-Y.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, December 2008, p. 3931-3934, Vol. 46, No. 12
0095-1137/08/$08.00+0     doi:10.1128/JCM.00577-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Molecular Epidemiological Identification of Neisseria gonorrhoeae Clonal Clusters with Distinct Susceptibility Profiles Associated with Specific Groups at High Risk of Contracting Human Immunodeficiency Virus and Syphilis{triangledown}

Wing-Wai Wong,2 Chung-Ter Huang,1 Lan-Hui Li,2 Chien-Chou Chiang,2 Bor-Dong Chen,1 and Shu-Ying Li1*

Research and Diagnostic Center, Centers for Disease Control, Taipei, Taiwan,1 Branch for Disease Control and Prevention, Taipei City Hospital, Taipei, Taiwan2

Received 26 March 2008/ Returned for modification 13 June 2008/ Accepted 1 October 2008

From April 2006 to August 2007, a total of 146 Neisseria gonorrhoeae isolates collected from 139 male patients in Taipei, Taiwan, were analyzed by N. gonorrhoeae multiantigen sequence typing (NG-MAST) and antibiotic susceptibility testing. The resistance rates of all isolates to ciprofloxacin, cefpodoxime, and cefixime were 76.7 (112/146), 21.2 (31/146), and 16.4% (24/146), respectively. NG-MAST identified 71 sequence types (STs), of which 21 STs contained 2 to 21 isolates. The isolates that belonged to the three major ST clusters typically were from patients who had specific epidemiological characteristics (such as sexual orientation and human immunodeficiency virus status). The major ST clones exhibited distinct resistance profiles and are associated with specific groups at high risk of human immunodeficiency virus and syphilis infections.

* Corresponding author. Mailing address: Research and Diagnostic Center, Centers for Disease Control, No. 161, Kun-Yang Street, Taipei, Taiwan. Phone: 886-2-26531388. Fax: 886-2-26513572. E-mail: syl{at}cdc.gov.tw

{triangledown} Published ahead of print on 8 October 2008.

Journal of Clinical Microbiology, December 2008, p. 3931-3934, Vol. 46, No. 12
0095-1137/08/$08.00+0     doi:10.1128/JCM.00577-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Monfort, L., Caro, V., Devaux, Z., Delannoy, A.-S., Brisse, S., Sednaoui, P. (2009). First Neisseria gonorrhoeae Genotyping Analysis in France: Identification of a Strain Cluster with Reduced Susceptibility to Ceftriaxone. J. Clin. Microbiol. 47: 3540-3545 [Abstract] [Full Text]  
  • Pandori, M., Barry, P. M., Wu, A., Ren, A., Whittington, W. L. H., Liska, S., Klausner, J. D. (2009). Mosaic Penicillin-Binding Protein 2 in Neisseria gonorrhoeae Isolates Collected in 2008 in San Francisco, California. Antimicrob. Agents Chemother. 53: 4032-4034 [Abstract] [Full Text]  
  • Tapsall, J W (2009). Implications of current recommendations for third-generation cephalosporin use in the WHO Western Pacific Region following the emergence of multiresistant gonococci. Sex. Transm. Infect. 85: 256-258 [Abstract] [Full Text]  
  • Tapsall, J. MD (2009). Multidrug-resistant Neisseria gonorrhoeae. CMAJ 180: 268-269 [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»