This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tan, L.-T.
Right arrow Articles by Cui, Z.-Z.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tan, L.-T.
Right arrow Articles by Cui, Z.-Z.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, February 2008, p. 750-753, Vol. 46, No. 2
0095-1137/08/$08.00+0     doi:10.1128/JCM.01587-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Molecular Characterization of Three New Virulent Newcastle Disease Virus Variants Isolated in China{triangledown}

Lei-Tao Tan,1 Huai-Ying Xu,1 You-Ling Wang,1 Zhuo-Ming Qin,1* Lei Sun,2 Wen-Jun Liu,2 and Zhi-Zhong Cui3

Institute of Poultry Science, Shandong Academy of Agricultural Sciences, Jinan 250100, China,1 Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China,2 College of Animal Science and Technology, Shandong Agricultural University, Taian 271018, China3

Received 9 August 2007/ Returned for modification 16 October 2007/ Accepted 13 November 2007

Three cases of Newcastle disease virus (NDV) found in nature had the lentogenic motif 112G-R-Q-G-R-L117 in their fusion protein cleavage sites. However, both intracerebral pathogenicity and intravenous pathogenicity indexes showed that these NDV isolates were virulent. In comparison with the LaSota live virus vaccine, these viruses had significant genetic variations in the hemagglutinin-neuraminidase gene.

* Corresponding author. Mailing address: Institute of Poultry Science, Shandong Academy of Agricultural Sciences, 58, Northern Road of Huangtai, Jinan 250100, China. Phone and fax: 86-531-88961344. E-mail: qinzm1997{at}163.com

{triangledown} Published ahead of print on 5 December 2007.

Journal of Clinical Microbiology, February 2008, p. 750-753, Vol. 46, No. 2
0095-1137/08/$08.00+0     doi:10.1128/JCM.01587-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»