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Journal of Clinical Microbiology, March 2008, p. 1106-1109, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.01877-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Characterization of Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Clinical Strains Collected from 2004 to 2007{triangledown}

Chao Qi,1,2* Michael Malczynski,2 Michelle Parker,2 and Marc H. Scheetz3,4

Department of Pathology, Northwestern University Feinberg School of Medicine,1 Clinical Microbiology Laboratory, Northwestern Memorial Hospital,2 Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy,3 Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois4

Received 20 September 2007/ Returned for modification 5 December 2007/ Accepted 14 January 2008

Genotypes of carbapenem-resistant Acinetobacter baumannii collected by the clinical microbiology laboratory of a university hospital in Chicago, IL, between 2004 and 2007 were analyzed by pulsed-field gel electrophoresis. A single genotype established predominance after being introduced in 2005. Analysis of carbapenemases by PCR revealed that imipenem resistance but not meropenem resistance was associated with the presence of blaOXA-23 and blaOXA-40 genes.

* Corresponding author. Mailing address: Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611. Phone: (312) 926-2181. Fax: (312) 926-4559. E-mail: cqi451{at}northwestern.edu

{triangledown} Published ahead of print on 23 January 2008.

Journal of Clinical Microbiology, March 2008, p. 1106-1109, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.01877-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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