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Journal of Clinical Microbiology, March 2008, p. 1137-1140, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.01991-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Detection of Echovirus 18 in Human Breast Milk{triangledown}

Marcela V. Maus,1 Michael A. Posencheg,2 Kristin Geddes,3 Michael Elkan,3 Silvia Peñaranda,4 M. Steven Oberste,4 and Richard L. Hodinka3*

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104,1 Division of Neonatology, Children's Hospital of Philadelphia, Hospital of the University of Pennsylvania, and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104,2 Departments of Pediatrics and Pathology and Clinical Virology Laboratory, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104,3 Polio and Picornavirus Laboratory Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 303334

Received 9 October 2007/ Returned for modification 29 November 2007/ Accepted 8 January 2008

We detected enteroviral RNA and cultured infectious virus from a series of banked breast milk samples from the mother of an infant with neonatal sepsis; sequencing of the enterovirus isolate identified it as echovirus type 18. In this case, it is possible that enterovirus transmission occurred through the breast milk.


* Corresponding author. Mailing address: Clinical Virology Laboratory, 716D Abramson Research Center, Children's Hospital of Philadelphia, 3615 Civic Center Blvd., Philadelphia, PA 19104. Phone: (215) 590-2028. Fax: (215) 590-2556. E-mail: hodinka{at}email.chop.edu

{triangledown} Published ahead of print on 16 January 2008.


Journal of Clinical Microbiology, March 2008, p. 1137-1140, Vol. 46, No. 3
0095-1137/08/$08.00+0     doi:10.1128/JCM.01991-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.