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Journal of Clinical Microbiology, June 2008, p. 2060-2061, Vol. 46, No. 6
0095-1137/08/$08.00+0     doi:10.1128/JCM.02300-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Catalase-Negative Staphylococcus aureus Strain with Point Mutations in the katA Gene{triangledown}

C. Piau,1 J. Jehan,2 R. Leclercq,1* and C. Daurel1

Service de Microbiologie, Université de Caen Basse-Normandie, CHU Côte de Nacre, 14033 Caen cedex,1 Laboratoire de Biologie, Centre hospitalier public du Cotentin—Hôpital de Valognes, 50700 Valognes, France2

Received 29 November 2007/ Returned for modification 7 December 2007/ Accepted 24 March 2008

Methicillin-susceptible catalase-negative Staphylococcus aureus strain UCN61 was isolated from an arterial leg ulcer. The deduced sequence of the structural katA gene for the catalase was 99% identical to those of other S. aureus strains. Two mutations were identified in katA from S. aureus UCN61, including one leading to a substitution of key histidine 58 by a tyrosine.


* Corresponding author. Mailing address: CHU de Caen, Service de Microbiologie, avenue Côte de Nacre, 14033 Caen cedex, France. Phone: (33) 02 31 06 45 72. Fax: (33) 02 31 06 45 73. E-mail: leclercq-r{at}chu-caen.fr

{triangledown} Published ahead of print on 2 April 2008.


Journal of Clinical Microbiology, June 2008, p. 2060-2061, Vol. 46, No. 6
0095-1137/08/$08.00+0     doi:10.1128/JCM.02300-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.