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Journal of Clinical Microbiology, July 2008, p. 2381-2383, Vol. 46, No. 7
0095-1137/08/$08.00+0     doi:10.1128/JCM.00801-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Impact of mecA Gene Testing and Intervention by Infectious Disease Clinical Pharmacists on Time to Optimal Antimicrobial Therapy for Staphylococcus aureus Bacteremia at a University Hospital{triangledown}

Peggy L. Carver,1* Shu-Wen Lin,2,{dagger} Daryl D. DePestel,1 and Duane W. Newton3

University of Michigan Health System and College of Pharmacy,1 Departments of Pharmacy Services and Clinical Sciences, University of Michigan Health System,2 Clinical Microbiology Laboratories and Department of Pathology, University of Michigan Health System and Medical School, Ann Arbor, Michigan3

Received 28 April 2008/ Accepted 29 April 2008

In patients with Staphylococcus aureus bacteremia, intervention by infectious disease clinical pharmacists on the basis of the results of tests for mecA resulted in a 25.4-h reduction in the time to optimal antimicrobial therapy, from 64.7 ± 36.8 to 39.3 ± 15.5 h (P = 0.002), which may result in decreased mortality.

* Corresponding author. Mailing address: Department of Clinical Sciences, University of Michigan College of Pharmacy, 428 Church Street, Ann Arbor, MI 48109-0008. Phone: (734) 764-9384. Fax: (734) 763-2022. E-mail: peg{at}umich.edu

{triangledown} Published ahead of print on 7 May 2008.

{dagger} Present address: National Taiwan University Hospital and Graduate Institute of Clinical Pharmacy, Taipei, Taiwan.

Journal of Clinical Microbiology, July 2008, p. 2381-2383, Vol. 46, No. 7
0095-1137/08/$08.00+0     doi:10.1128/JCM.00801-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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