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Journal of Clinical Microbiology, January 2009, p. 217-219, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01506-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Comparison of Cefoxitin and Oxacillin Disk Diffusion Methods for Detection of mecA-Mediated Resistance in Staphylococcus aureus in a Large-Scale Study{triangledown}

Nicole M. Broekema, Tam T. Van, Timothy A. Monson, Steven A. Marshall, and David M. Warshauer*

Wisconsin State Laboratory of Hygiene, Communicable Disease Division, 465 Henry Mall, Madison, Wisconsin 53706

Received 5 August 2008/ Accepted 10 November 2008

The recommended breakpoints for the cefoxitin disk diffusion test for Staphylococcus aureus were recently modified. In this large-sample study, cefoxitin sensitivity and specificity compared to those of oxacillin were 97.3% and 100%, respectively. This study validated the new cefoxitin breakpoints for the detection of mecA-mediated resistance in S. aureus.

* Corresponding author. Mailing address: Wisconsin State Laboratory of Hygiene, Communicable Disease Division, 465 Henry Mall, Madison, WI 53706. Phone and fax: (608) 265-9115. E-mail: warshadm{at}slh.wisc.edu

{triangledown} Published ahead of print on 19 November 2008.

Journal of Clinical Microbiology, January 2009, p. 217-219, Vol. 47, No. 1
0095-1137/09/$08.00+0     doi:10.1128/JCM.01506-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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