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Journal of Clinical Microbiology, April 2009, p. 1229-1230, Vol. 47, No. 4
0095-1137/09/$08.00+0     doi:10.1128/JCM.02424-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Predicting Clearance of Colonization with Vancomycin-Resistant Enterococci and Methicillin-Resistant Staphylococcus aureus by Use of Weekly Surveillance Cultures{triangledown}

Charmaine M. Huckabee,1 W. Charles Huskins,2 and Patrick R. Murray3*

Rho Federal Systems Division, Inc., Chapel Hill, North Carolina,1 College of Medicine, Mayo Clinic, Rochester, Minnesota,2 National Institutes of Health Clinical Center, Bethesda, Maryland3

Received 17 December 2008/ Returned for modification 6 February 2009/ Accepted 17 February 2009

We analyzed surveillance cultures for vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) collected during a multicenter trial to determine if three negative cultures collected at weekly intervals would predict clearance of VRE or MRSA from colonized patients. Seventy-two percent of VRE-colonized patients and 94% of MRSA-colonized patients were culture negative after three consecutive negative cultures.

* Corresponding author. Mailing address: NIH Clinical Center, 10 Center Drive, Dept. Lab. Med., Room 2C385, Bethesda, MD 20892. Phone: (301) 402-9559. Fax: (301) 402-1886. E-mail: pmurray{at}cc.nih.gov

{triangledown} Published ahead of print on 25 February 2009.

Journal of Clinical Microbiology, April 2009, p. 1229-1230, Vol. 47, No. 4
0095-1137/09/$08.00+0     doi:10.1128/JCM.02424-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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