This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wirden, M.
Right arrow Articles by Calvez, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wirden, M.
Right arrow Articles by Calvez, V.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, May 2009, p. 1543-1545, Vol. 47, No. 5
0095-1137/09/$08.00+0     doi:10.1128/JCM.02134-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Impact of Discrepancies between the Abbott RealTime and Cobas TaqMan Assays for Quantification of Human Immunodeficiency Virus Type 1 Group M Non-B Subtypes{triangledown}

M. Wirden,1,2* R. Tubiana,2,3 F. Marguet,3 I. Leroy,1 A. Simon,4 M. Bonmarchand,4 Z. Ait-Arkoub,1 R. Murphy,3 A. G. Marcelin,1,2 C. Katlama,2,3 and V. Calvez1,2

Department of Virology, Pitié-Salpêtriere Hospital, Paris, France,1 Inserm U943, Paris, France,2 Department of Infectious Diseases, Pitié-Salpêtriere Hospital, Paris, France,3 Department of Internal Medicine, Pitié-Salpêtrière Hospital, Paris, France4

Received 7 November 2008/ Returned for modification 13 January 2009/ Accepted 9 March 2009

Viral loads in 249 clinical samples from individual patients infected with human immunodeficiency virus type 1 non-B subtypes were determined with both the Abbott RealTime and Cobas TaqMan assays. The differences exceeded 0.5 log for about 20% of samples and 1 log for 3%, with higher values always from the Abbott assay in the latter cases.

* Corresponding author. Mailing address: Laboratoire de Virologie, Hôpital Pitié-Salpêtrière, Bât. CERVI, 75013 Paris, France. Phone: 33 1 42 17 74 09. Fax: 33 1 42 17 74 11. E-mail: marc.wirden{at}psl.aphp.fr

{triangledown} Published ahead of print on 18 March 2009.

Journal of Clinical Microbiology, May 2009, p. 1543-1545, Vol. 47, No. 5
0095-1137/09/$08.00+0     doi:10.1128/JCM.02134-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Delaugerre, C., Denis, B., Peytavin, G., Palmer, P., Mourez, T., Le Goff, J., Molina, J.-M., Simon, F. (2009). Clinical and Resistance Consequences of Misquantification of Plasma and Cerebrospinal Fluid Human Immunodeficiency Virus Type 1 (HIV-1) RNA in Samples from an HIV-1 Subtype G-Infected Patient. J. Clin. Microbiol. 47: 3763-3764 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»