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Journal of Clinical Microbiology, May 2009, p. 1602-1604, Vol. 47, No. 5
0095-1137/09/$08.00+0     doi:10.1128/JCM.01932-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Brain Abscess Caused by Tsukamurella tyrosinosolvens in an Immunocompetent Patient{triangledown}

Wang-Huei Sheng,1,2 Yu-Tsung Huang,3 Shan-Chwen Chang,2 and Po-Ren Hsueh2,3*

Department of Internal Medicine, Far-East Memorial Hospital,1 Department of Internal Medicine,2 Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan3

Received 6 October 2008/ Returned for modification 23 November 2008/ Accepted 11 March 2009

We describe a previously healthy patient with chronic otitis media complicated with cerebellar abscess caused by Tsukamurella tyrosinosolvens. The organism was identified based on conventional biochemical identification methods, PCR-restriction fragment length polymorphism analysis of the hsp65 gene, and 16S rRNA gene sequencing. The patient was treated successfully with debridements and prolonged antibiotic therapy.


* Corresponding author. Mailing address: Depts. of Laboratory Medicine and Internal Medicine, National Taiwan University, No. 7 Chung-Shan S. Rd., 100 Taipei, Taiwan. Phone: 886-2-3123456, ext. 65355. Fax: 886-2-23224263. E-mail: hsporen{at}ntu.edu.tw

{triangledown} Published ahead of print on 18 March 2009.


Journal of Clinical Microbiology, May 2009, p. 1602-1604, Vol. 47, No. 5
0095-1137/09/$08.00+0     doi:10.1128/JCM.01932-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.