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J. Clin. Microbiol. doi:10.1128/JCM.00104-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Molecular epidemiology of the streptococcal invasive locus (sil) in group A streptococci causing invasive infections in French children

Université Paris VII, UFR médicale; EA 3105, laboratoire d'Études de Génétique Bactérienne dans les Infections de l'Enfant; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Microbiologie, Laboratoire associé au CNR des Streptocoques - Infections à Streptocoque du groupe A de l'enfant, Hôpital Robert Debré, Paris, France

^* To whom correspondence should be addressed. Email: edouard.bingen{at}rdb.ap-hop-paris.fr.

	Abstract

We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children, The predominant emm-types were emm1 (25%), emm3 (8%), emm4 (8%), emm6 (7%) and emm89 (9%). Sixteen percent of isolates harbored the streptococcal invasive locus, half of them belonging to emm4.

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• Billal, D. S., Hotomi, M., Shimada, J., Fujihara, K., Ubukata, K., Sugita, R., Yamanaka, N. (2008). Prevalence of Streptococcus Invasive Locus (sil) and Its Relationship with Macrolide Resistance among Group A Streptococcus Strains. J. Clin. Microbiol. 46: 1563-1564 [Full Text]