JCM Accepts, published online ahead of print on 11 October 2006
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J. Clin. Microbiol. doi:10.1128/JCM.00621-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Feasibility of freeze-dried sera for serological and molecular biological detection of hepatitis B and C viruses

Waka Ohishi*, Saeko Fujiwara, Gen Suzuki, Takeshi Kishi, Misae Sora, Shinsuke Matsuura, Masayuki Hakoda, Yoshimi Tatsukawa, Michiko Yamada, and Kazuaki Chayama

Department of Clinical Studies, Radiation Effects Research Foundation, 5-2 Hijiyama Park, Minami-ku, Hiroshima, 732-0815, Japan; Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan

* To whom correspondence should be addressed. Email: nwaka{at}rerf.or.jp.


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Abstract

We compared hepatitis B surface antigen, anti-hepatitis C virus (HCV) antibody, and HCV RNA quantification in frozen and freeze-dried serum samples to assess the usefulness of freeze-dried sera for detection of hepatitis B virus (HBV) and HCV. The results indicated that freeze-dried sera as well as frozen sera can be useful for serological and molecular biological analyses of HBV and HCV.




This article has been cited by other articles:

  • Ohishi, W., Fujiwara, S., Cologne, J. B., Suzuki, G., Akahoshi, M., Nishi, N., Takahashi, I., Chayama, K. (2008). Risk Factors for Hepatocellular Carcinoma in a Japanese Population: A Nested Case-Control Study. Cancer Epidemiol. Biomarkers Prev. 17: 846-854 [Abstract] [Full Text]  


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