JCM Accepts, published online ahead of print on 3 July 2007

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J. Clin. Microbiol. doi:10.1128/JCM.00715-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Investigation into the Stability of Multiple-Locus Variable-Number Tandem-Repeats in Salmonella enterica serovar Typhimurium

K. L. Hopkins^*, C. Maguire, E. Best, E. Liebana, and E. J. Threlfall

Laboratory of Enteric Pathogens, Health Protection Agency Centre for Infections, London, United Kingdom; Veterinary Laboratories Agency, Addlestone, Surrey, United Kingdom

^* To whom correspondence should be addressed. Email: katie.hopkins{at}hpa.org.uk.

Variable-Number Tandem-Repeats (VNTRs) may evolve so rapidly that multiple profiles emerge during an outbreak. 190 isolates from eight Salmonella Typhimurium outbreaks and 15 isolates from seven patients were analyzed by PFGE and VNTR-typing. Small changes in loci were noted, otherwise VNTR profiles were stable during the course of the outbreaks.

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