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JCM Accepts, published online ahead of print on 31 October 2007
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J. Clin. Microbiol. doi:10.1128/JCM.01055-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Comparison of the HIV-1 specific IgG capture ELISA (BED-CEIA) with the avidity index method for identification of recent HIV-infections

Stephan Loschen, Jörg Bätzing-Feigenbaum, Gabriele Poggensee, Christiane Cordes, Bettina Hintsche, Michael Rausch, Stephan Dupke, Silvia Gohlke-Micknis, Jana Rödig, Osamah Hamouda, and Claudia Kücherer*

Robert Koch-Institut, Project HIV Variability and molecular epidemiology, Berlin, Germany; Robert Koch-Institut; Dept. HIV/AIDS and STI; Berlin, Germany; Medical Practice, Berlin, Germany

* To whom correspondence should be addressed. Email: KuechererC{at}rki.de.


  Abstract

The sensitivity and specificity of the HIV-1-specific IgG capture ELISA (BED-CEIA) were compared with those of the avidity index method to identify recent HIV infection using a panel of 148 samples (81 patients) representing durations of infection ranging from zero to 222 weeks. The results from the two tests were similar (sensitivity: 80% versus 74%, p=0.53; specificity: 86% versus 82%, p=0.67).




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Copyright © 2007 by the American Society for Microbiology. All rights reserved.