Identification of Adenoviruses from High Risk Pediatric Stem Cell Transplant Recipients and Controls

Children's Memorial Hospital, Northwestern Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, and Centers for Disease Control and Prevention, Atlanta, Georgia

^* To whom correspondence should be addressed. Email: x-zheng{at}northwestern.edu.

	Abstract

Adenovirus infection is an important cause of morbidity and mortality in stem cell transplant recipients. We report species and type-specific analysis from a prospective study of high-risk adenovirus infections following hematopoietic progenitor cell transplantation prior to, during and after treatment with cidofovir as well as species analysis from contemporaneously collected control patients. Nine different adenovirus types representing all 6 recognized species were identified and mixed infections were commonly found in this group of patients.